Over 10 years ago, C&C biotech pharmaceutical company developed technologies that provided site selective carriers the opportunity to target specific organs, tissues, and receptor sites. The fundamental property found in C&C-Nutrients is the delivery of nutrients with their naturally occurring Protein Vital Carrier (PVC).
In 1995, C&C developed and marketed food type nutrients called C&C-Nutrients. Later on, as recently as 1997, new discoveries revealed the delivery path of nutrients. We now know the details of the nutrient delivery mechanism. The knowledge has changed our thinking about nutrition perpetually.
Protein Vital carrier (PVC), targeting gastro-intestinal tract transporters, is designed to allow large molecules such as protein/peptides to be given orally rather than by injection. These products are based on the focused application of proprietary processes which improve uptake of such nutrients as vitamins and minerals in the small intestine. These targeted protein/peptides have been successfully utilized to deliver nutrients to specific sites.
The use of Protein Vital Carrier (PVC) has been confirmed by the awarding of the 1999 Nobel Prize in Physiology to Dr. Gunter Blobel and the published work of Dr. Thomas O’Halloran in 1997.
The next breakthrough in nutritional science was the awarding of the 1999 Noble Prize in Physiology to Dr. Gunter Blobel for discovering that proteins have intrinsic signals that govern their transport and localization in the cell.
Dr. Blobel, a cell and molecular biologist at Rockefeller University in New York, has been researching the molecular mechanisms underlying the processes by which proteins are directed or transported into the cell.
Dr. Blobel discovered that proteins have inherent signal that is essential for governing them to and across the cellular membranes. He also showed that similar, “address tages” or “Zip codes”, direct proteins to other intracellular locations. We call these intrinsic codes Protein Vital Carrier (PVC).
Each protein carries in its structure the information needed to specify its proper location in the cell. The principles discovered and described by Gunter Blobel are universal operating similarly in single cell plant, plant, and animal cells. Blobel attested that “the knowledge of protein carriers will increase our understanding of processes leading to disease and can be used to develop new therapeutic strategies. Currently both drugs and nutrients are being produced with protein carriers, e.g. insulin, growth hormone, interferon and C&C-Nutrients.
The principles discovered by Dr. Blobel have significance when we consider the ability of plants, such as Saccharomyces cerevisiae (nutritional baker’s yeast), and Lactobacillus bulgaricus (yogurt), to transform inorganic substances into forms that readily utilized in the human physiology. C&C-Nutrients follows the exact same principles. This transformation fixes the carriers to the nutrient an dprovides them with addresses and zip codes which allow them to be delivered to the appropriate cell receptor sites.
The inherent Protein Vital Carrier found in C&C-Nutrients are a major link to the way the body absorbs, transports, stores, and assimilates nutrients. This decisive discovery of the delivery of nutrients to cells was announced just a few years ago at Northwestern University, Johns Hopkins University and the University of Michigan and confirmed with the awarding of the 1999 Nobel Prize for Physiology. These findings indicate that nutrients are not simply floating around in the body looking for a needy cell. Rather, they are being transported by Protein Vital Carriers to the exact location for utilization within the cell.
The most critical aspect of vitamin and mineral supplement delivery is Protein Vital Carriers. The quantity of nutrient consumed does not directly equate to the quantity of the nutrient utilized.
In most cases where high quantities of vitamins and minerals are administered the reverse is true. The total capacity of the protein carriers to deliver the nutrient into the cell is the major consideration in determining the tatal quantity of nutrient assimilated into the cells.
The advantage of providing nutrients in the C&C-Nutrients state is that the nutrients are in a form requiring no changes, therefore saving vital energy. When nutrients are whole, with naturally occurring complete proteins and other phyto-nutrients, they are in a form that is readily used by the human physiology. The Vital Food factors that are essential for carrying out this function are the Protein Vital Carriers.
C&C® Nutrients is based on the work of US scientist, Dr. J Vinson who developed proprietary processes to concentrate micronutrients into food complexes. Professor J Vinson from Scranton University in Pennsylvania has been involved for many years in conducting trials comparing isolated chemicals and C&C® Nutrients. His summanry expresses the important elements of this unique and remarkable technology.
The technology is supported by recent research, including work by Nobel Prize winner, Dr. Gunter Blobel.
These C&C® Nutrients are essentially foods and are recognized by the body as such. These 21st century nutrients are the first supplements that can truly be called food supplements.
C&C® supplements have the nutritional components and structure of real food. The unique and outstanding feature of C&C® nutrients is the complete imbedding of the micronutrients into a food matrix. This does not mean physically mixing the vitamins and minerals with proteins and other substances. Rather it involved a sophisticated “growing” process.
This question had plagued scientists for many years.
A significant breakthrough in nutritional science was the awarding of The 1999 Noble Prize in Physiology to Dr. Gunter Blobel for discovering that proteins have intrinsic signals that govern their transport and localization in the cell.
Dr. Blobel, a cell and molecular biologist at Rockefeller University in New York, has been researching the molecular mechanisms underlying the processes by which proteins are directed or transported into the cell.
Dr. Blobel discovered that proteins have an “intrinsic signal” that is essential for governing them to and across the cellular membranes.
One scientist struggled to answer this question when he found that although scurvy could be cured by eating oranges or limes.. But the active ingredient (ascorbic acid) did nothing when taken as an isolated supplement.
After years researching the answer to this questions, Dr. Gunter Blobel discovered that nutrients inside food are bound by many other essential elements, such as protein, carbohydrates, and lipids. These other binding elements are called carrier co-factors (CCF).
Nutrients occur naturally as complex food compounds and it is in this form that they best support the body’s processes.
Dr. Blobel found that the protein co-factors performed a remarkable function:
He discovered that protein contain unique signals that act like a cellular “Zip Code” in localizing and transporting their attached nutrients to particular cells that they need them. The proteins are called protein chaperones.
Protein chaperones exist naturally in whole food and accompany nutrients to the cells that need them. Therefore, as many as there are nutrients, there are many different corresponding protein chaperones. The type of each protein chaperone depends on which vitamin or mineral needs to be transported to the corresponding cells.
If our scurvy-curing scientist (at the beginning) had learned of Dr. Blobel's discovery, he would have realized that Vitamin C, taken without its carrier cofactors found in oranges and limes, lacked its appropriate protein chaperones and that deprived bodily cells were unable to absorb a helpful amount of the ingested mineral.
In short, only when eaten as whole food could the person or animal utilize enough of the nutrient (ascorbic acid) well enough to cure scurvy.
Proteins have “intrinsic Signals” which act as“address tags” or “Zip Code”, directing proteins to particular sites.
Isolated chemical nutrients are foreign to the body. Their effectiveness is vastly inferior to their natural counterparts and there is some evidence that they may even confuse or override the natural processes.
In the image (above): a protein chaperone Binds and delivers Vitamin C to a signaling cell. Peptide chains with particular amino acid sequences constitute these protein-specific signals. The signal will determine whether a protein will pass through a membrane to a particular site within the cell (organelle) or be exported out of the cell.
The active nutrient is “fed” into the most suitable plant medium for it; that is, the most suitable plant matter with the enzymes to digest it fully. For example, citrus pulp is used for the “re-naturing”of ascorbic acid, because it is naturally high in vitamin C receptor sites; carrot pulp is used with Beta Carotene; alfalfa with Vitamin K, and so on. The enzymes naturally present in the various mediums integrate the vitamin so thoroughly; it is fully incorporated into a food matrix or food state.
We know inorganic, mineral substances cannot be manufactured within the body, but must be absorbed into our bodies through the food chain.
C&C® feeds the inorganic mineral into living plant cells, which absorb them, re-naturing them once again into a fully bonded food matrix.
Both the vitamin and mineral products are harvested, freeze dried and tabletted, following a strictly monitored procedure, to ensure that nothing (e.g. Heat, or pressure during manufacture), can interfere with their availability to the body’s natural digestive processes, thus providing the body with an eminently highly effective and bio-available form of supplementation.
Absorption is an over-used and often abused word. Most people who take food supplements are “sold” that one brand is better absorbed than other. Absorption, however, is not the complete story.
Bioavailability covers absorption, retention, assimilation and utilization. Unless the supplement is high in all of these factors, the real benefit to our body can be very low. There is only little benefit if the isolated nutrient, having been absorbed into td stream, cannot be assimilated by a solid organ such as the liver. If it is not assimilated, it cannot be retained or utilized on demand. The nutrient must also be delivered to the right place.
This means that isolated chemical nutrients may be absorbed, but when they enter the body there is no mechanism to target their delivery. The body does not recognize them. So, they are either deposited in the wrong places, which causes problems, or they are flushed right back out of the body.
C&C® nutrients on the other hand are delivered by the protein chauffeurs to the cells that need the nutrients and, more specifically, to the right sites within the cells.
Nutrients occur naturally as complex food compounds and it is in this form that they best support the body’s processes.
Isolated chemical nutrients are foreign to the body. Their effectiveness is vastly inferior to their natural counterparts and there is some evidence that they may even confuse or override the natural processes.
This means that isolated chemical nutrients may be absorbed, but when they enter the body there is no mechanism to target their delivery. The body does not recognize them. So, they are either deposited in the wrong places, which causes problems, or they are flushed right back out of the body. C&C nutrients on the other hand are delivered by the protein chauffeurs to the cells that need the nutrients and, more specifically, to the right sites within the cells.
C&C® nutrients are whole food concentrates that are nutrient dense and highly bioavailability. They are a complex matrix of proteins, carbohydrates, dietary fiber, enzymes, active bioflavonoids and thousands of bio-active food compounds.
Human study bio-availability
Nuclear Magnetic Resonance (NMR) Waveforms
Electron Microscope
The following is a summary of the results (protocols available )of some of the many individual nutrients studies on human subjects.
The term “absorption” refers to the relative increase over baseline in the amount of the nutrients in the blood.
The term “retention” refers to the relative increase in the amount stored in the liver.
The graphs of the results of the studies performed at University of Scranton by Dr. Joe A. Vinson et. Show the data as provided by the researchers, which indicates comparative levels by assigning the USP group an arbitrary value of 100% bioavailability and plotting the C&C® organic group’s relative level.
Resveratrol
In Blood: 1210% more absorbed than “pure” USP after 24 hours.
In Liver: 560% more retained than “pure” USP after 24 hours.
β-glucan
In Blood: 288% more absorbed than “pure” USP after 24 hours.
In Liver: 530% more retained than “pure” USP after 24 hours.
D-Ribose
In Blood: 454% more absorbed than “pure” USP after 24 hours.
In Liver: 256% more retained than “pure” USP after 24 hours.
Bioflavonids
In Blood: 1626% more absorbed than “pure” USP after 24 hours.
In Liver: 940% more retained than “pure” USP after 24 hours.
Zinc
In Blood: 646% more absorbed than “pure” USP after 24 hours.
In Liver: 368% more retained than “pure” USP after 24 hours.
Copper
In Blood: 144% more absorbed than “pure” USP after 24 hours.
In Liver: 185% more retained than “pure” USP after 24 hours.
Selenium
In Blood: 122% more absorbed than “pure” USP after 24 hours.
In Liver: 226% more retained than “pure” USP after 24 hours.
Iron
In Blood: 177% more absorbed than “pure” USP after 24 hours.
In Liver: 168% more retained than “pure” USP after 24 hours.
Toxicity: C&C® GTF chromium was found to be virtually non-toxic, whereas inorganic chromium is highly toxic.
C&C® GTF chromium reduced blood cholesterol levels, increased high-density lipoproteins, improved glucose control in diabetics, glycosylated hemoglobin became normal.
Comparison of Resveratrol in a pure isolated state to Resveratrol in a C&C® organic food state.
Nuclear Magnetic resonance (NMR) is the preeminent technique for determining the structure of organic compounds. NMR technique determines structural differences by a dynamic process that measures internal motions, or energy levels, within regions of larger molecules such as loops in a protein.The comparison clearly shows a structure and dynamic difference between a Resveratrol in C&C® organic food state and one in an isolated “pure” state. (Electron Microscope reveals the difference)
C&C® 100% whole food nutrients are visibly different from United States Pharmacopeia (USP) nutrients which are commonly referred to as “pure”. Notice the rounded, more natural shape of our C&C® nutrients. They are in a wholesome natural food form. Compare the size of the particles. C&C® particles are smaller and easier for the body to utilize as they pass through the digestive system. They utilized like wholesome natural food.
C&C Biotech Pharmaceuticals