About us

        C&C Biotech Pharmaceuticals is a joint venture between research & development partners in USA and distribution partners in Asia. C&C was a pioneer in research on aging, and now we’re a global leader in the field. Opened in 1999, we are the world’s only research center singularly focused on the biology of aging, yielding insights into age-related disease before they start. We hire scientists from a variety of disciplines to attack the problem from all sides because the answers we’re after won’t come from a single field. 


        The company has an R& D tie up with international universities from Australia, China,Taiwan and Japan. The highly advanced R&D unit at C&C is a complete research facility for phytochemistry, pharmacokinetics, formulation, development and pre-clinical studies. C&C’s state of the art laboratory has been approved for in-house research by the Ministry of Science & Technology in USA.

        Because of how we’re structured, how we conduct our research, and the elite collection of scientists we have working with us, C&C is in a unique position to define the approach for solving many of the biggest problems facing the world today. C&C ‘s leadership works every day to ensure our scientiss and doctors have the support and resources they need as they tackle these immense challenges.



Highly Advanced & Complete R&D Facility

        While Japanese firms spend 5-6 percent of their revenues on R&D, most of USA companies’ R&D expenditure was always at one percent or even lower. But C&C spends about 10% of its turnover in R&D.

        C&C feels that R&D focus is absolutely important for herbal extraction company to fight global majors and stay afloat. The only way to have a strong presence in the market is to have a pipeline of exciting launches which will require superior R&D.

        The highly advanced R&D unit at C&C is a complete research facility for phytochemistry, pharmacokinetics, formulation and development, pre-clinical and clinical studies. The laboratory employs advanced high-tech equipment like LC MS-MS (Waters, USA) which facilitates mass directed quantification and identification of molecules. Other high-tech equipment include the UPLC with ELS, FLR and PDA Detectors, GCMS, Preparative HPLC, Flash Chromatograph, HPLC and FTIR. For NMR and DNA finger printing studies, C&C associates with reputed universities. On top of it all, the processes are controlled and monitored by well experienced and highly qualified scientists. Other distinctive features include, specialized equipment for blood plasma analysis as well as a well maintained. The Greenhouse maintained here with many medicinal plants chimes in perfectly well with the rich heritage of traditional wisdom. 





         Liquid chromatography paired with a mass spectrum detector presents a dynamic tool for separation, identification and quantification of molecules. Whereas HPLC is a good isolation instrument, it is limited in its ability to provide pure, single chemical results. But by ionizing and then putting an isolate of interest through the Mass Spectrometer, its discriminant comparison against a database or standard makes identification much more precise. Additionally, this combination allows for isomer detection, which MS alone cannot provide. 1 



         Ultra Performance Liquid Chromatography optimizes the separation capacity of its 30-year predecessor, HPLC, by reducing the particle size of the sample and the flow pressure rate at which it is sensed. Eco-friendly increases in speed, sensitivity and resolution are achieved in this evolution of HPLC. Matched with a photo diode array (PDA) sensor, improved detection of trace impurities and sensitivity in quantitation of analyte is afforded. The precision of this instrument is used for setting standards for content or quality of important molecules/compounds. 2  



         A more flexible version of UPLC, allowing more autonomous control of speed, sensitivity and resolution by the researcher in separating, identifying and quantifying molecules. 3  



         As the name implies, Flash CG is a rapid purification technique similar to preparative HPLC. Suitable for bulk separation or for routine procedure, where the efficiency of separation is not of consequence, lower cost Flash CG is a viable alternative to HPLC. 4 



         Drying solvent-extracted naturally resourced samples is one of the most time-consuming processes in the pre-analytic and concentrating phases of product development. In remaining cutting-edge and innovative in this industry, time is of the essence. The Gen Vac EZ-2 vacuum evaporation system expedites this tedious process, so our research and development team can spend more time discovering “scientifically and clinically proven, consumer demanded ingredients.” 5  



Quality Control Along International Standards

        With the constant increase in the use of dietary supplements worldwide and the rapid expansion of the global market, the safety and quality of herbal materials and finished herbal products have become a major concern for health authorities, pharmaceutical industries and the public. The safety and efficacy of herbal extracts largely depend on their quality.

        Because of their often complex and variable nature, control of raw materials, storage and processing assume particular importance in the manufacture of herbal products. The raw materials are sourced from approved vendors so as to conform to standard specifications. These are then analyzed to ensure that active constituents are present as detailed in the QC manual. Our QA system ensures the consistency and quality of the finished products.

        C&C strengthened the laboratory facilities with many modern instruments and equipment like GC-MS for checking the presence of pesticides. Head space GC accurately analyses traces of residual solvents to meet the stringent specifications. C&C has been using Inductively Coupled Plasma Mass Spectrometry(ICP-MS)ever since it was introduced commercially and gained general acceptance in many types of laboratories. The lab staff and scientists have been trained in the use of this equipment and can detect traces of any metal. C&C uses other sophisticated testing equipment like HPTLC(Camag,Swiss) for complete finger printing of complex molecule.

        While the QA department tests chemical parameters and organoleptic qualities of all types of products, the modern microbiology laboratory functions for testing microbiological parameters of products.

        Close on the heels of a three-tier monitoring system, C&C has rolled out a quality control manual to further streamline quality assurance and quality control in its projects. The manual details the steps in line with the WHO guide lines to be followed while manufacturing, quality of materials to be used, and the testing procedures to be carried out. Besides, the specifications, methods to be adopted for ensuring quality have been listed out in detail.





         A four pole mass spectrometry device of high sensitivity, the Inductively Coupled Plasma-MS is particularly advantageous for trace determinations of metals like Pb, Cd, Hg, As, etc. and surveying for unknown or unexpected elements. The detection capability of 0.1 ppm at 1% wt. is superior to the often compared ICP-AES of the same sample type. Comparatively, the ICP-MS also has the ability to obtain information about isotopes, which are common for many elements and missed by traditional mass spectrometry.  



         A simple, fast and efficient upgrade to conventional Thin Layer Chromatography, this higher performance, automation-enhanced technique has improved the resolution and thus separation ability of plated analyses. A standard in the pharmaceutical industry, this advanced technique far surpasses more crude qualitative assessment procedures by providing reproducible, quantitative analyses important for fingerprinting and GMP conformity.  



         Gas Chromatography and Mass Spectrometry in combination specialize in separating out and quantifying volatile and semi-volatile analytes. Pesticide testing is a good example of its use. GC is a temperature-controlled process that separates out the components of a given sample by weight and size, while the MS characterizes and quantifies each component accordingly. GC MS is eco-friendly and performs at high speeds for increased productivity. 



          Headspace sampling is an automated addition to conventional GC, which allows for improved contrasting between volatile oils and other components in a given mixture. With a more refined sample, the purity and relative amounts of a particular substance in the mixture can be obtained with greater ease, speed and accuracy.  



        The high performance, preparative use of Liquid Chromatography isolates known or unknown compounds from a mixture for further study of structure, activity, toxicology, etc. This instrument advances the practice of traditional separation methods, like extraction, distillation or crystallization by using high flow rates and large columns for precise and pure outputs. HPLC can be used for compound analysis, but lacks the sensitivity required to tease out compounds that are structurally very similar. For this reason, our lab defers to more sensitive instrumentation in analyzing the HPLC isolated compounds.